Clinical efficacy of prophylactic clipping of mucosal defects after endoscopic removal for large colorectal neoplasms

Interventions: Medical Device : After endoscopic removal of colon polyps larger than 2 cm, the mucosal defect is closured with a clips Primary outcome(s): Complication ( delayed bleeding, delayed perforation, post electrocoagulation syndrome );Complication associated clipping ( hemorrhage, perforation) Primary Purpose : Prevention, Intervention Model : Parallel, Blinding/Masking : Single, Blinding Target : Subject, Allocation : RCT