Data from: Access to SCF3 substituted indolizines via a photocatalytic late-stage functionalization protocol
收藏DataCite Commons2026-01-29 更新2026-04-25 收录
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https://datadryad.org/dataset/doi:10.5061/dryad.v6wwpzh7x
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资源简介:
A mild, scalable, and highly chemoselective photocatalytic method was
developed for the direct indolizine functionalization with
N-((trifluoromethyl)thio)saccharin, yielding high amounts of desired
products while tolerating various functional groups. The photoredox
catalyst employed offers a straightforward and inexpensive alternative to
commercially available catalysts. Additionally, a 3-SCF₃ analogue of a
histamine H3 receptor antagonist was synthesized with excellent yield,
demonstrating the strategy’s potential in developing biologically relevant
molecules.
提供机构:
Dryad
创建时间:
2025-07-31



