CPPsite: a curated database of cell penetrating peptides

Welcome to the documentation for CPPsite, a comprehensive and manually curated database of experimentally validated cell-penetrating peptides (CPPs). This resource is designed to centralize information scattered across literature and patents to help researchers understand the properties of these peptides and develop effective delivery vehicles for therapeutic molecules. Database URL: https://webs.iiitd.edu.in/raghava/cppsite1/ Citation Gautam, A., Singh, H., Tyagi, A., Chaudhary, K., Kumar, R., Kapoor, P., & Raghava, G. P. S. (2012). CPPsite: a curated database of cell penetrating peptides. Database, Vol. 2012, Article ID bas015. https://doi.org/10.1093/database/bas015 About the Database CPPsite provides systematic information on 843 experimentally validated CPP entries, derived from 741 unique sequences. These peptides have the unique ability to cross the eukaryotic plasma membrane, which is otherwise selectively permeable and often impermeable to large therapeutic molecules like DNA and proteins. The database integrates data from: Research Articles: Over 500 articles were searched, with 83 selected for high-quality experimental data. Patents: 50 patents were searched, with 20 utilized for the database.