Profiles of mRNA and lncRNA expression in colorectal cancer. Profiles of mRNA and lncRNA expression in colorectal cancer

Colorectal cancer (CRC) is one of the most malignant cancers with high morbidity and mortality. Genetic factors are involved in the carcinogenesis of CRC, which consists of a complex accumulation of mutations in key regulatory genes and epigenetic regulation.Here we report significantly up-regulated as well as down-regulated mRNAs and lncRNAs in CRC tissues compared with their matched non-tumoral tissues. Overall design: Examination of Differential Expression of mRNAs and lncRNAs between 3 pairs of colorectal tumor tissues and normal tissues