Skin Microbiome in Atopic Dermatitis. Skin Microbiome in Atopic Dermatitis

Atopic dermatitis significantly affects the composition of the microbiome, not only in eczematous lesional skin, but also in normal appearing, non-lesional skin and the nose, suggesting a more global effect of the disease. In the study skin and nasal samples were collected from adult Atopic dermatitis patients (n=58) and healthy volunteers (n=46) in Denmark. Amplicon sequencing of the 16S rRNA (V3V4) gene was performed in order to investigate the bacterial communities (Causen et al. 2017, doi: 10.1001/jamadermatol.2017.5440) and amplicon sequensing of the 18S rRNA (V3-V5) gene was performed in order to investigate the eukaryotic microbial communities (Edslev et al. 2021, doi: 10.21203/rs.3.rs-116456/v1).