The genes involved in EMT.

The majority of the genes' expressions, except GSC, TJP1 and MMP3, indicate further malignant development of the early onset cancer group. Surprisingly, E-cadherin was down-regulated by more than 5 fold in the cancer patients. 1The value is the median of log2-scaled expressions of the group. 2The value is the fold-change of the cancer samples over the healthy controls. 3The genes refer to Knutson et al. [36]. 4The genes refer to Polyak et al. [9]. 5It is the normal-appearing mucosa in the CRC patients.