Effects of dietary with Extraction of Atractylodes macrocephala Koidz on growth performance, health, and disease resistance of Macrobrachium nipponense

Despite the rapid development of Macrobrachium nipponense, disease problems in intensive farming have become increasingly serious, resulting in lower production. Atractylodes macrocephala Koidz has the effect of anti-pathogenic and anti-vira, is not easily resistant to drugs, and has the ability to promote the growth aspect of animals and improve immunity. In order to better improve the growth performance and disease resistance of aquaculture animals, it is necessary to develop herbal-based feed additives in the aquatic products. Taking Macrobrachium nipponense as the research object, this paper explores the effects of extraction of Atractylodes macrocephala Koidz (EAMK) as herbal additives on growth, health and disease resistance, and provides a scientific basis for the development and application of aquatic green feed additives.In this paper, we investigated the effects of feeding different levels of EAMK on production performance, organ index, blood biochemical index, antioxidant capacity, digestive health and disease resistance of Macrobrachium nipponense. The experiment was conducted on Macrobrachium nipponense with an initial body weight of 0.21 g. Six feed treatments were set up with the addition of EAMK at 0, 100, 200, 400, 600 and 1200 mg/kg (Control, A100, A200, A400, A600 and A1200). Each feed treatment was set up with 6 replicates, 60 shrimp were placed in each tank, and the experimental period was 75 days. The feeding status of the test Japanese marsh shrimp was observed daily during the experiment, water temperature, pH, and ammonia nitrogen concentration in the water and the amount of food taken in each replicate tank was recorded. At the end of the experiment, serum, intestine, hepatopancreas were collected.Data were expressed as mean ± standard error (mean±SE), and the results were performed using SPSS 21.0 software for one-way ANOVA with a significant level of (P<0.05), followed by multiple comparisons using Duncan's method. Quadratic polynomial fit of WGR to the level of leucous extract addition.