Single-cell chromatin accessibility of anti-viral CD4 T cells in Bcl6 and Blimp1 deficient conditions

Single-cell chromatin accessibility of effector CD4+ T cells WT or Bcl6 Blimp1-deficient was determined by scATACseq after LCMV Armstrong infection Overall design: Mixed bone marrow chimera made of WT, Bcl6-deficient , Blimp1-deficient or Bcl6 Blimp1-deficient cells were infected with LCMV Armstrong. 7 days post-infection GP66+ CD4+ T cells were sorted and chromarin accessibility was determined by scATACseq