crystal structure of BCL-2 G101V mutation with S55746
收藏Protein Data Bank Japan2023-10-11 更新2026-03-21 收录
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crystal structure of BCL-2 G101V mutation with S55746 Descriptor: Apoptosis regulator Bcl-2,Bcl-2-like protein 1,Apoptosis regulator Bcl-2, ~{N}-(4-hydroxyphenyl)-3-[6-[[(3~{S})-3-(morpholin-4-ylmethyl)-3,4-dihydro-1~{H}-isoquinolin-2-yl]carbonyl]-1,3-benzodioxol-5-yl]-~{N}-phenyl-5,6,7,8-tetrahydroindolizine-1-carboxamide Authors: Birkinshaw, R.W, Luo, C.S, Colman, P.M, Czabotar, P.E. Deposit date: 2019-02-17 Release date: 2019-05-22 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.998 Å) Cite: Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations. Nat Commun, 10, 2019
创建时间:
2019-02-17



