Short Total Synthesis of (+)-Madindolines A and B
收藏NIAID Data Ecosystem2026-03-06 收录
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https://figshare.com/articles/dataset/Short_Total_Synthesis_of_-Madindolines_A_and_B/3741255
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资源简介：
A short and efficient total synthesis of (+)-madindolines A (1) and B (2), potent and selective inhibitors of interleukin 6, has been achieved.
The synthesis features a key chelation-controlled 1,4-diastereoselective acylation to generate the quaternary carbon and an intramolecular
acylation of allylsilane to build up the cyclopentene unit.
创建时间：
2016-08-20
