Gene expression data of the liver in hepatocyte-specific Phgdh knockout mice. Gene expression data of the liver in hepatocyte-specific Phgdh knockout mice

Live hepatocyte-specific Phgdh KO (LKO) mice were generated by introducing Albumin-Cre transgene into Phgdh flox/flox (Floxed) mice. LKO mice exhibited mild obesity and impaired glucose intolerance at 30 weeks old. Overall design: Total RNA was extracted from the liver of LKO and littermate Floxed mice (male, 30 weeks old, n = 6, each genotype) . Six biological replicates for each treatment were used for amplification and labeling for Agilent microarray platform.