Human brain microvascular endothelial cells, adult cortical cells (hBMVECs, CellSystems, Kirkland, WA, USA used at passage 3 cultured and harvested as described in Proteomic and metabolomic character
This study aimed to establish the human UGT transcriptome landscape by UGT-targeted mRNA sequencing. UDP-glucuronosyltransferases (UGTs) are key enzymes involved in the metabolism and detoxification o
d = doublet, s = singlet, m = multiplet. Percentage of variation was calculated for each patient as the area of the spectral region or selected XCMS feature at baseline minus the area of the same feat
Cytochrome P450 oxidoreductase (POR) is involved in the oxidative metabolism of xenobiotics and endogenous compounds like fatty acid and cholesterol. While effects of diminished Por were extensively s