five

First bromodomain of BRD4 liganded with compound 2c

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Protein Data Bank Japan2023-10-18 更新2026-04-19 收录
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First bromodomain of BRD4 liganded with compound 2c Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, prop-2-en-1-yl (5S)-1-ethyl-7-methyl-5-(4-methylphenyl)-2,4-dioxo-1,2,3,4,5,8-hexahydropyrido[2,3-d]pyrimidine-6-carboxylate Authors: Schonbrunn, E, Chan, A. Deposit date: 2022-04-28 Release date: 2022-08-24 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.55 Å) Cite: 1,4-Dihydropyridinebutyrolactone-derived ring-opened ester and amide analogs targeting BET bromodomains. Arch Pharm, 355, 2022
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2022-04-28
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