Interferon Alpha (IFNα) Induction and Knockout Analysis of ISGs in Atlantic Salmon SHK-1 Cells Challenged with ISAV and IPNV. Interferon Alpha (IFNα) Induction and Knockout Analysis of ISGs in Atlantic Salmon SHK-1 Cells Challenged with ISAV and IPNV

To investigate differentially expressed genes (DEGs) upon challenge with infectious salmon anemia virus (ISAV) or infectious pancreatic necrosis virus (IPNV) after IFNα treatment, in comparison to untreated cells. To examine the differentially expressed genes (DEGs) in knock-out (KO) cells with specific IFN receptors knockout, following IFNα treatment and infection with ISAV or IPNV. The expression profiles of these KO cells were compared with non-KO cells also treated with IFNα and infected with ISAV or IPNV.