Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with TR06772818
收藏Protein Data Bank Japan2025-09-24 更新2026-04-19 收录
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Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with TR06772818 Descriptor: Casein kinase II subunit alpha, SULFATE ION, ~{N}-[5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-4-fluoranyl-2-[(3~{S})-3-(methylamino)piperidin-1-yl]phenyl]propanamide Authors: Kraemer, A, Ong, H.W, Yang, X, Brown, J.W, Chang, E, Willson, T, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2024-07-03 Release date: 2024-09-11 Last modified: 2025-09-24 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Strategic Fluorination to Achieve a Potent, Selective, Metabolically Stable, and Orally Bioavailable Inhibitor of CSNK2. Molecules, 29, 2024
创建时间：
2024-07-03
