WP4971 - Phosphoinositides metabolism - Homo sapiens

Phosphatidylinositols are a family of lipids under the phosphatidylglyceride class. This pathway specifies several metabolic conversions between PIP, PIP2, PIP3 and other metabolites. Phosphorylation sites on the individual metabolites are drawn as states, with the location added as a number.

The main interactions within this pathway are based on Figure 1 of [Rusten et al.](https://doi.org/10.1038/nmeth867), annotated with biochemical interaction database [Rhea](https://www.rhea-db.org/), and diseases (depicted in pink) with corresponding [OMIM-identifiers](https://www.omim.org/). Dashed lines depict proposed interactions which have not been characterized (yet).