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Mapping of autologous neutralization specificity by Env inhibition.

Figshare2016-09-28 更新2026-04-29 收录

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Mapping of autologous neutralization specificity by Env inhibition.

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2016-09-28

HIV中和抗体

病毒检测技术

This protocol describes a pseudovirus assay that measures neutralization of HIV, SIV and SHIV as a function of reductions in Tat-regulated Luc reporter gene expression after a single round of infectio

Harvard Dataverse2018-09-08 更新40

International Network for Comparison of HIV Neutralization Assays: The NeutNet Report II

HIV中和抗体

疫苗免疫原性

BackgroundNeutralizing antibodies provide markers for vaccine-induced protective immunity in many viral infections. By analogy, HIV-1 neutralizing antibodies induced by immunization may well predict v

Figshare2016-01-19 更新30

Crystal structure of anti-HIV-1 V3 Fab 3074 in complex with a UR29 V3 peptide

蛋白质晶体学

HIV中和抗体

Crystal structure of anti-HIV-1 V3 Fab 3074 in complex with a UR29 V3 peptide

NIAID Data Ecosystem20

Neutralization sensitivity of the isogenic V3 recombinant HIV-1 to anti-gp120 monoclonal antibodies.

HIV中和抗体

gp120蛋白

#Neutralization epitope in the Gp120 outer domain before CD4 binding.$Neutralization epitope induced in Gp120 after CD4 binding.*Epitopes outside of the CD4 binding site [37].@The effect of each antib

Figshare2015-12-02 更新30

Representation of the GE356 Fab crystal structure and paratope mapping analysis.

抗体工程

HIV中和抗体

(A) The GE356 heavy chain is shown in dark blue and light chain in light blue. The HCDR and LCDR loops are colored as follows: CDR1s (green), CDR2s (orange), CDR3s (magenta). (B) Effects of alanine su

NIAID Data Ecosystem30

Mapping of autologous neutralization specificity by Env inhibition.

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