The role of BRCT domain from LmjPES in Leishmania major biology

To investigate the implications of LmjPES BRCT domain overexpression in Leishmania major. We generated a strain of L. major constitutively overexpressing LmjPES BRC domain and we compared its gene expression with other L. major strain no-overexpressing this domain.The data showed a role of LmjPES BRC domain in genes related mainly to metabolic patways Overall design: Comparative gene expression profiling analysis of RNA-seq data for Leishmania major overexpressing and no-overexpressing LmjPES BRCT domain