Proteins with lower or higher expression upon depletion of TgNFS2 as found by label-free quantitative proteomics.

For each protein candidate (with www.ToxoDB.org and www.Uniprot.org identifier), log2 of the different ratio were calculated between the mean MaxQuant LFQ values (‘moyLFQ’) found for the TgISU1 (‘Mito’) and TgNFS2 (‘Apicoplast’) mutants, and the TATi ΔKu80 control (‘CTRL’). -log10(pvalue) is also provided. Putative subcellular localization was obtained from the hyperLOPIT data available on ToxoDB.org, or by manual annotation. CRISPR fitness score and transcriptomic data for tachyzoites (Tz) and bradyzoites (Bz) were obtained from ToxoDB.org.
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