TFAP2A
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https://rgd.mcw.edu/rgdweb/report/gene/main.html?id=1321067
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资源简介：
The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009]
该基因编码的蛋白质为一种转录因子，可结合一致序列5'-GCCNNNGGC-3'。该编码蛋白可形成同源二聚体或与家族中其他成员形成异源二聚体。此蛋白可激活某些基因的转录，同时抑制其他基因的转录。该基因的缺陷是分支眼面综合征（BOFS）的发病原因。对于该基因，已发现三种转录变体，分别编码不同的异构体。[由RefSeq提供，2009年12月]
提供机构：
Rat Genome Database
