Two mixed-ligand Cd(II)-coordination polymers: structural diversity and antitumor activity against human osteogenic sarcoma cells
收藏DataCite Commons2024-02-19 更新2024-07-28 收录
下载链接：
https://tandf.figshare.com/articles/dataset/Two_mixed-ligand_Cd_II_-coordination_polymers_structural_diversity_and_antitumor_activity_against_human_osteogenic_sarcoma_cells/11860935/1
下载链接
链接失效反馈官方服务：
资源简介：
A systematic investigation into the reactions of Cd(NO<sub>3</sub>)<sub>2</sub>·4H<sub>2</sub>O with o- and p-phenylenediacetic acid within the presence of the semi-rigid 1,4-bis(imidazol-1-ylmethyl)benzene (bimb) co-ligands under similar conditions was carried out. In this study, two novel coordination polymers containing Cd(II) ions as the metal ions {[Cd(μ-opda)(bimb)]·DMF}<sub>n</sub> (<b>1</b>, opda = 1,2-phenylenediacetate) and [Cd(μ-ppda)(bimb)<sub>0.5</sub>]<sub>n</sub> (<b>2</b>, ppda = 1,4-phenylenediacetate) have been prepared and structurally characterized. Furthermore, the inhibitory function of these two synthetic complexes on MG-63 human osteogenic sarcoma cells was evaluated with cell counting kit-8. And the Annexin V-FITC/PI apoptosis detection was performed to detect the induction ability of the complexes on the cancer cell apoptosis. Then, the western blot was performed to measure the activation level of the PTEN-AKT pathway.
提供机构：
Taylor & Francis
创建时间：
2020-02-17
