Structure of a small molecule inhibitor with the kinase domain of Chk2
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Structure of a small molecule inhibitor with the kinase domain of Chk2 Descriptor: 4-(1H-pyrazol-5-yl)-2-{4-[(3S)-pyrrolidin-3-ylamino]quinazolin-2-yl}phenol, NITRATE ION, SERINE/THREONINE-PROTEIN KINASE CHK2 Authors: Caldwell, J.J, Welsh, E.J, Matijssen, C, Anderson, V.E, Antoni, L, Boxall, K, Urban, F, Hayes, A, Raynaud, F.I, Rigoreau, L.J, Raynham, T, Aherne, G.W, Pearl, L.H, Oliver, A.W, Garrett, M.D, Collins, I. Deposit date: 2010-07-26 Release date: 2011-01-12 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure-Based Design of Potent and Selective 2-(Quinazolin-2-Yl)Phenol Inhibitors of Checkpoint Kinase 2. J.Med.Chem., 54, 2011
创建时间:
2010-07-26



