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HSF1 promotes proliferation and chemoresistance in diffuse large B-cell lymphoma by enhancing cell cycle and DNA repair

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE295838
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To further elucidate the mechanism of HSF1-mediated transcriptional regulation in diffuse large B-cell lymphoma, we conducted transcriptomic sequencing on SU-DHL-2 and SU-DHL-6 cells treated with or without DTHIB (8 μM). Diffuse large B-cell lymphoma cells SU-DHL-2 or SU-DHL-6 were treated with DMSO or DTHIB (8 μM) for 36 hours. The RNA of the treated cells was extracted and sequenced on Illumina NovaseqTM 6000 platform and 100-bp paired-end reads were generated.
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2025-07-23
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