Impact of Cleansing With Chlorhexidine Gluconate (CHG) on Reducing Central Line Associated Bloodstream Infection (CLABSI) and Acquisition of Multi-drug Resistant Organisms (MDRO) in Children With Cancer or Those Receiving Allogeneic Hematopoietic Cell Transplantation (HCT)

This randomized phase III trial studies chlorhexidine gluconate cleansing to see how well it
works compared to control cleansing in preventing central line associated bloodstream
infection and acquisition of multi-drug resistant organisms in younger patients with cancer
or undergoing donor stem cell transplant. Chlorhexidine gluconate may help reduce bloodstream
infections and bacterial infections associated with the central line.