SETD7 in complex with inhibitor (R)-PFI-2 and S-adenosyl-methionine
收藏Protein Data Bank Japan2023-09-20 更新2026-03-21 收录
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SETD7 in complex with inhibitor (R)-PFI-2 and S-adenosyl-methionine Descriptor: 8-fluoro-N-{(2R)-1-oxo-1-(pyrrolidin-1-yl)-3-[3-(trifluoromethyl)phenyl]propan-2-yl}-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide, Histone-lysine N-methyltransferase SETD7, S-ADENOSYLMETHIONINE, ... Authors: Dong, A, Wu, H, Zeng, H, El Bakkouri, M, Barsyte, D, Vedadi, M, Tatlock, J, Owen, D, Bunnage, M, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Structural Genomics Consortium (SGC) Deposit date: 2013-03-12 Release date: 2013-04-17 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.896 Å) Cite: (R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells. Proc.Natl.Acad.Sci.USA, 111, 2014
创建时间：
2013-03-12
