Micro-aberration Frequency by Gene.

A) The top 17 genes that displayed the most micro-aberrations are shown, along with the number of micro-aberrations (All)/micro-amplifications (Amp)/micro-deletions (Del) seen within each gene. The expected number of micro-aberrations for each gene, corrected for gene size, is calculated based on the distribution of log2 ratio values for our dataset and the probability of observing a segment meeting our micro-aberration cutoffs. p-values calculated by Chi-square test.*Based on the distribution of log-ratio data within our dataset and the probability given this distribution of contiguous probes meeting the cutoffs for micro-aberrations, with correction for gene size.**p-value based on Chi-square test.