Mark Cooper (2011) CIL:37332, epidermal cell. CIL. Dataset

This is a migrating epidermal cell showing vigorous lamellipodial ruffling more than 180 degrees around its circumferance. The cell becomes elongated into a canoe shape. The mechanical tension generated by the lamellipodia appears to stretch the cell into an elongated form. The lamellipodia in the anterior region of the cell are opposed by a lamellipodium in the trailing region of the cell. This may account for the persistance of the cells motion in a forward direction. All of the cells organelles-- lysozomes, mitochondria, endoplasmic reticulum--are localized with microtubules around the cell body at the trailing edge of the cell. Video made available by Mark Cooper thru Zebrafish - The Living Laboratory.

本数据集展示了一例正在迁移的表皮细胞，其周边区域呈现超过180度的强烈板状伪足波动。细胞形态拉长，形成类似独木舟的形状。板状伪足产生的机械张力似乎将细胞拉伸成长形。细胞前端的板状伪足与后端的板状伪足相抗衡，这可能解释了细胞向前运动持续性的原因。所有细胞器——如溶酶体、线粒体、内质网——均定位于细胞尾端周围的细胞质微管上。该视频由Mark Cooper提供，通过斑马鱼——生命实验室制作。