Integrin alphaMbeta2 (MAC1) binds JAM3

Recruitment of monocytic cells to the vessel wall by platelets is mediated via CD11b/CD18 (Mac-1) and platelet JAM-C. In the case of dendritic cells, this interaction leads to their activation and platelet phagocytosis. This process may be of importance for progression of atherosclerotic lesions.

单核细胞被血小板招募至血管壁的过程是通过CD11b/CD18（Mac-1）和血小板JAM-C介导的。在树突状细胞的情况下，这种相互作用会导致其活化及血小板吞噬作用。此过程对于动脉粥样硬化病变的进展可能具有重要意义。