five

Bace1 with the aminohydantoin Compound S-34

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Protein Data Bank Japan2024-10-16 更新2026-03-21 收录
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Bace1 with the aminohydantoin Compound S-34 Descriptor: (5S)-2-amino-5-(4-methoxy-3-methylphenyl)-3-methyl-5-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]-3,5-dihydro-4H-imidazol-4-one, Beta-secretase 1 Authors: Olland, A.M, Chopra, R. Deposit date: 2009-08-12 Release date: 2010-03-02 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.996 Å) Cite: Design and synthesis of 5,5'-disubstituted aminohydantoins as potent and selective human beta-secretase (BACE1) inhibitors. J.Med.Chem., 53, 2010
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2009-08-12
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