Gene expression profiling in VRK1-deficient testis of Mus musculus

To study effect of VRK1 deletion on spermatogenesis of the mouse, transciptomic analysis of genes in postnatal 8-day testicular cells of wild type and VRK1-deficient Mus musculus was performed. Gene expression in testes from from wild type and VRK1-deficient mutant Mus musculus, respectively, was measured. Four independent experiments for wild type and mutant, respectively, were performed.为探究VRK1基因敲除对小鼠精子发生的影响，本研究对野生型及VRK1缺陷型小家鼠（Mus musculus）出生后8天的睾丸细胞进行了转录组学分析。分别检测了野生型与VRK1缺陷型小家鼠睾丸组织的基因表达水平。本研究分别为野生型组与突变型组各开展了四次独立重复实验。