Similarities and Distinctions in Actions of Surface-Directed and Classic Androgen Receptor Antagonists

ChEBI2015-12-31 更新2026-07-12 收录

激素受体拮抗剂

药物作用机制比较

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Similarities and Distinctions in Actions of Surface-Directed and Classic Androgen Receptor Antagonists

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2015-12-31

Performance Standards For Stably Transfected Transactivation In Vitro Assays To Detect Estrogen Receptor Antagonists ‑ Second edition

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This document includes the Performance Standards (PS) for stably transfected transactivation in vitroassays to detect estrogen receptor (ER) antagonists. These PS accompany the Performance-Based Test

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Discovery of N ‑(thiazol-2-yl) Furanamide Derivatives as Potent Orally Efficacious AR Antagonists with Low BBB Permeability

泌尿生殖系统癌症药物

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Resistance-conferring mutations in the androgen receptor (AR) ligand-binding pocket (LBP) compromise the effectiveness of clinically approved orthosteric AR antagonists. Targeting the dimerization int

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Genome-Wide Progesterone Receptor Binding: Cell Type-Specific and Shared Mechanisms in Uterine Fibroids and Breast Cancer (Expression BeadChip)

基因表达调控

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Analysis of genes regulated by RU486 (an progesterone antagonist) in human breast cancer T47D cells and human uterine leiomyoma smooth muscle cells. The hypothesis is that RU486 inhibits tumor growth

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1,4-Substituted Triazoles as Nonsteroidal Anti-Androgens for Prostate Cancer Treatment

抗前列腺癌药物研发

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Prostate cancer (PC) is the fifth leading cause of cancer death in men, and the androgen receptor (AR) represents the primary target for PC treatment, even though the disease frequently progresses tow

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Selective estrogen receptor downregulator antagonists: Tetrahydroisoquinoline phenols 1.

药物化学

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Selective estrogen receptor downregulator antagonists: Tetrahydroisoquinoline phenols 1. Descriptor: (E)-3-[4-[(1R,3R)-6-hydroxy-2-isobutyl-3-methyl-3,4-dihydro-1H-isoquinolin-1-yl]phenyl]prop-2-enoic

Protein Data Bank Japan2024-05-08 更新30

Similarities and Distinctions in Actions of Surface-Directed and Classic Androgen Receptor Antagonists

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