Data for Figshare.xlsx

Twenty Holstein cows received a common prepartal diet and postpartal diet. Both diets were partially supplemented with an inorganic (INO)mix of Zn, Mn, and Cu to supply 35, 45, and 6 ppm, respectively, of the diet dry matter. Cows were assigned to treatments in a randomized completed block design, receiving a daily oral bolus with inorganic or organic trace minerals (AAC) Zn, Mn, Cu, and Co to achieve 75, 65, 11, and 1 ppm supplemental, respectively, in the entire diet dry matter. Liver tissue and blood samples were collected at -30, -15, 10, and 30 d and -30, -14, 3, 15, and 30 d relative to parturition, respectively. Gene expression and biomarkers related to liver function, inflammation, oxidative stress, metabolism, and hepatokines were measured in liver and blood samples, respectively.