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TRIM21 knockout mouse livers show enhanced antioxidant capacity and decreased compensatory proliferation

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP300699
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Acute response to diethylnitrosamine treatment in TRIM21 wild-type and knockout mice were compared and differentially expressed genes were inendified at 48 hours Overall design: TRIM21 wild-type and knockout mice were treated with one dose of 200 mg/kg diethylnitrosamine (DEN) dissolved in PBS or PBS only by intraperitoneal injection, 48 h after the treatment, liver tissue were harvested and total RNA is extracted and sequenced
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2025-05-30
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