Application of the Illumina MethylationEPIC on small amount of fragmentized HCT116 genomic DNA. Application of the Illumina MethylationEPIC on small amount of fragmentized HCT116 genomic DNA

Cell-free DNA is generally in fragments around 200 bp. Genomic DNA from HCT116 cell is sonicated to around 200 bp to mimic cell-free DNA. This is a control assay to test the sensitivity of Infinium methylationEPIC array for low amount of fragmentized DNA. Overall design: The genomic DNA was extracted from HCT116 cell and sonicated to fragment around 200 bp. DNA methylation was detected by Infinium methylationEPIC array.