Dual C–H Functionalization of N‑Aryl Amines: Synthesis of Polycyclic Amines via an Oxidative Povarov Approach
收藏Figshare2015-12-17 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Dual_C_H_Functionalization_of_i_N_i_Aryl_Amines_Synthesis_of_Polycyclic_Amines_via_an_Oxidative_Povarov_Approach/2033277
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Iminium ions generated in situ via copper(I) bromide catalyzed oxidation of N-aryl amines readily undergo [4 + 2] cycloadditions with a range of dienophiles. This method involves the functionalization of both a C(sp3)–H and a C(sp2)–H bond and enables the rapid construction of polycyclic amines under relatively mild conditions.
创建时间:
2015-12-17



