Human EGFR-mutant lung cancer cells lines were investigated for their dynamic transcriptional response upon treatment with EGFR-inhibitor osimertinib in a time-series experiment
Analysis of the characteristics of the transcriptome in human squamous cell lung carcinomas. This study also provided a deeper understanding of the role of transcriptome in LUSC survival.
Purpose: The aim of this study is to build up a transcriptomic data analysis pipeline and test its performance using synthetic "sequins" controls and lung cancer cell lines. Methods - Cell Culture: Lu
To analyze how RAB39A-inhibition can affect cancer stemness, in 143B and HeLa cell spheres, we have transcriptionally profiled the poorly grown cancer-spheres (RAB39A-knockdowns, shRAB(4) and (5)), in