Sex-biased effects on hippocampal circuit development by perinatal SERT expression in CA3 pyramidal neurons
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE214392
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We demonstrate in mice that perinatal SERT expression in glutamatergic pyramidal neurons in the hippocampus and mPFC modulates sexually dimorphic gene expression during hippocampal circuit assembly and is a source for sex-biased susceptibilities to cognitive and behavioral impairments. Comparative gene expression profiling analysis of RNA-seq data from dorsal hippocampal tissues dissected from P7 SERTPyramid and SERTfl/fl control pups in three replicates; each replicate consisted of dorsal hippocampus tissue pooled from four mice.
创建时间：
2023-01-04
