Tear Proteome Analysis Using LC-MS/MS in Patients with Primary Nasolacrimal Duct Obstruction

The pathogenesis of primary acquired nasolacrimal duct obstruction (PANDO) remains unclear, with several factors implicated, including anatomical structures, hormones, and tear components. This study explores tear proteins to better understand PANDO etiology by comparing protein expression in tears from PANDO patients and healthy controls.