Supplementary Tables - Tomono et al.xlsx

Variations of blood concentration levels of reactive carbonyls among three case-control studies of breast and colorectal cancer: Interactions with proteins and nucleic acids of lipid aldehydes, which contribute to oxidative stress signals, are associated with cancer development. The aim of the present study was to identify novel biomarkers for the detection of a high-risk group and/or early disease diagnosis, and to elucidate the roles of lipophilic reactive carbonyls (RCs) on the development of breast and colorectal cancers. In the present study, a comprehensive method was applied for analysis of RCs in plasma/serum samples. Higher concentrations of cis-4-decenal were noted in colorectal and breast cancers, suggesting that they may be candidate biomarkers for high-risk groups and/or early diagnosis.