The SNP-involved, miRNA mediated, post-transcriptional regulation modules (SNP-MPRMs) in the YRI population.

SNP: The SNP located in a predicted miRNA targets site in the 3′ UTR region of the corresponding gene; Mutation: DS indicates that the target site predicted from the reference sequence (hg18) is disrupted due to the nucleotide substitution, and CR indicates that a novel target site is created due to the substitution; TSE: miRNA target site effect on gene expression level; adj.p: FDR corrected p-value for TSE; miRNA: the MiRBase ID of a human miRNA with the corresponding SNP in the predicted target site. The common prefix “hsa-mir(let)-” in the IDs is omitted. The rows in bold indicate the regulation modules shared by both CEU and YRI populations. See method section for the calculation of TSE. Disease genes are indicated by asterisks (*).