IL17A homodimer complexed to Compound 23
收藏Protein Data Bank Japan2024-11-13 更新2026-04-19 收录
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IL17A homodimer complexed to Compound 23 Descriptor: Interleukin-17A, ~{N}-[(2~{S})-1-[[(1~{S})-1-(8~{a}~{H}-imidazo[1,2-a]pyrimidin-2-yl)ethyl]amino]-1-oxidanylidene-4-phenyl-butan-2-yl]-4,5-bis(chloranyl)-1~{H}-pyrrole-2-carboxamide Authors: Argiriadi, M.A, Ramos, A.L. Deposit date: 2023-10-29 Release date: 2024-04-03 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.83 Å) Cite: Discovery of Small Molecule Interleukin 17A Inhibitors with Novel Binding Mode and Stoichiometry: Optimization of DNA-Encoded Chemical Library Hits to In Vivo Active Compounds. J.Med.Chem., 67, 2024
创建时间：
2023-10-29
