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Application of Off-Rate Screening in the Identification of Novel Pan-Isoform Inhibitors of Pyruvate Dehydrogenase Kinase

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Protein Data Bank Japan2024-01-17 更新2026-03-21 收录
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https://pdbj.org/mine/summary/5m4n
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Application of Off-Rate Screening in the Identification of Novel Pan-Isoform Inhibitors of Pyruvate Dehydrogenase Kinase Descriptor: CHLORIDE ION, N-(2-AMINOETHYL)-2-{3-CHLORO-4-[(4-ISOPROPYLBENZYL)OXY]PHENYL} ACETAMIDE, [2,4-bis(oxidanyl)phenyl]-[(2~{S})-2-methyl-6-(3-methylquinolin-2-yl)-3,4-dihydro-2~{H}-quinolin-1-yl]methanone, ... Authors: Baker, L.M, Brough, P, Surgenor, A. Deposit date: 2016-10-18 Release date: 2017-02-22 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Application of Off-Rate Screening in the Identification of Novel Pan-Isoform Inhibitors of Pyruvate Dehydrogenase Kinase. J. Med. Chem., 60, 2017
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2016-10-18
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