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Crystal structure of the human neutral sphingomyelinase 2 (nSMase2) catalytic domain with insertion deleted and calcium bound

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Protein Data Bank Japan2024-03-06 更新2026-03-21 收录
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Crystal structure of the human neutral sphingomyelinase 2 (nSMase2) catalytic domain with insertion deleted and calcium bound Descriptor: CALCIUM ION, Sphingomyelin phosphodiesterase 3,Sphingomyelin phosphodiesterase 3 Authors: Airola, M.V, Guja, K.E, Garcia-Diaz, M, Hannun, Y.A. Deposit date: 2017-02-20 Release date: 2017-06-28 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.849 Å) Cite: Structure of human nSMase2 reveals an interdomain allosteric activation mechanism for ceramide generation. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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2017-02-20
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