Patient Characteristics (initial presentation)

aAge at presentation in years; dc, deceased;bHF, chronic heart failure; NYHA, classi-fication of heart failure according to the New York Heart Association; CD, cardiac deathcEA, Ebstein's anomaly;dASD, atrial septal defect;eaECG, abnormal ECG;fNVM, non-compaction of the ventricular myocardium; +, affected; (+), partially affected; see Material and Methods for details on the affection status; non-isolated/isolated: with/without EA and/or ASD. Listed are all carriers of the MYH7 mutation and in addition individual III-2 who was not genotyped.