Crystal structure of CDK2 bound by compound 4
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Crystal structure of CDK2 bound by compound 4 Descriptor: (2R)-2-[(9-isopropyl-6-{[(3S)-1-(methylsulfonyl)-3-pyrrolidinyl]amino}-9H-purin-2-yl)amino]-3-methyl-1-butanol, Cyclin-dependent kinase 2 Authors: Collie, G.W, Pflug, A. Deposit date: 2024-09-03 Release date: 2025-09-10 Last modified: 2025-09-24 Method: X-RAY DIFFRACTION (1.16 Å) Cite: Discovery of AZD8421: A Potent CDK2 Inhibitor with Selectivity Against Other CDK Family Members and the Human Kinome. J.Med.Chem., 68, 2025
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2024-09-03
