Automatically obtained PLM biomarkers in Stanford Sleep Cohort.

PLM metrics are calculated from PLM classified using our detector (SNR+). PLM/h and periodicity indices are calculated for wake (PLMW/h) and sleep (PLMS/h). Patients having more two hours of evaluation were grouped according to sleep pathology as determined by formal medical diagnosis. The circadian effect is reversed in narcolepsy, with PLM more likely to occur during the second half of the sleep study, and less extreme in insomnia where PLM are only slightly more frequent (i.e. 33%) in the first half of the study.Data are mean ± Standard Error Mean, or percentage. The number of subject used for calculations are shown in parentheses. Probabilities (p) are calculated using one-way analysis of variance between groups with a 0.05 significance level. See Fig. 4 for description of terms.Automatically obtained PLM biomarkers in Stanford Sleep Cohort.