ena-DATASET-MRCHGUIGMM-20-11-2018-10:51:14:897-153 - samples

NIAID Data Ecosystem2026-03-10 收录

小头畸形侏儒症遗传学

DNMT3A

数据链接：

https://www.omicsdi.org/dataset/ega/EGAD00001004470 数据链接链接失效反馈

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资源简介：

Exome sequence data from microcephalic dwarfism patients with de novo DNMT3A variantsEGA dataset EGAD00001004470

创建时间：

2018-11-30

Isoform-specific localization of DNMT3A regulates DNA methylation fidelity at bivalent CpG islands [5-hMeDIP]

DNA甲基化

DNMT3A

DNA methylation is a prevalent epigenetic modification involved in transcriptional regulation and essential for mammalian development. While the genome-wide distribution of this mark has been studied

干细胞与再生医学数据中心2022-02-20 更新80

Somatic Dnmt3a deletion in murine hematopoietic cells

肿瘤表观遗传学

DNMT3A

Mutations in the gene encoding DNA methyltransferase 3A (DNMT3A) are the most common cause of clonal hematopoiesis, and among the most common initiating events for acute myeloid leukemia (AML). This m

NIAID Data Ecosystem40

Supplementary Table S6 from DNMT3A Haploinsufficiency Transforms FLT3 ITD Myeloproliferative Disease into a Rapid, Spontaneous, and Fully Penetrant Acute Myeloid Leukemia

急性髓系白血病

DNMT3A

DMR in DNMT3A rescued c-Kit+ Flt3ITD/ITD;Dnmt3afl/fl MxCre cells versus c-Kit+ Flt3ITD/ITD;Dnmt3afl/fl MxCre empty vector control cells.

NIAID Data Ecosystem20

Expression data from DNMT3A in human gastric cancer

胃癌基因表达

DNMT3A

DNA methylation is a major epigenetic mechanism that plays an important role in the early tumorigenic process.However, little is known about the roles of DNA methyltransferase 3A (DNMT3A) in gastric c

NIAID Data Ecosystem60

RNASeq of K562 cell clones for DNMT3A-WT, DNMT3A-W305*, DNMT3A-R882H, DNMT3A-R882C

克隆造血

DNMT3A

Donor blood saves lives, yet the potential impact of recurrent large-volume phlebotomy on donor health and hematopoietic stem cells (HSCs) remains largely unexplored. In our study, we conducted a comp

NIAID Data Ecosystem20

ena-DATASET-MRCHGUIGMM-20-11-2018-10:51:14:897-153 - samples

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