Microarray analyses of mouse dorsal root ganglia tissue for six different pain models

ChEBI2018-06-11 更新2026-07-12 收录

疼痛模型基因表达

神经组织微阵列分析

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Microarray analyses of mouse dorsal root ganglia tissue for six different pain models

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2018-06-11

Expression data from pain model: rat L5 sensory ganglia after local inflammation. Rattus norvegicus

疼痛模型基因表达

炎症机制

Inflammation plays a role in neuropathic pain conditions as well as in pain induced solely by an inflammatory stimulus. Robust mechanical hyperalgesia and allodynia can be induced by locally inflaming

NIAID Data Ecosystem30

FACS purified Nav1.8 lineage sensory neuron whole transcriptome changes following peripheral inflammation (CFA) or sciatic nerve injury (SNI).. FACS purified Nav1.8 lineage sensory neuron whole transcriptome changes following peripheral inflammation (CFA) or sciatic nerve injury (SNI).

伤害感受神经元转录组

疼痛模型基因表达

The goal of this study was to analyze global gene expression in FACS purified Nav1.8 lineage sensory neurons, which include nociceptor neurons that detect damaging/noxious stimuli, following periphera

NIAID Data Ecosystem10

High-throughput unbiased RNA-Sequencing (RNA-Seq) to profile gene expression in ipsilateral L4-L6 DRG obtained from rats of Sham+Veh, CPIP+Veh and CPIP+ETA groups

炎症机制

疼痛模型基因表达

Since TNF-α is a pro-inflammatory cytokine that can promote neuroinflammation to mediate chronic pain, we then explored which signaling molecules or pathways in DRG were affected by TNF-α and contribu

NIAID Data Ecosystem00

Mus musculus Raw sequence reads

疼痛模型基因表达

小鼠变异位点分析

The study was carried out to study the gene expression level, differential gene enrichment analysis and variation site analysis of SNL pain model mice.

NIAID Data Ecosystem20

Comparison to other DRG microarray studies.

疼痛模型基因表达

神经损伤微阵列

Abbreviations: Affy, Affymetrix. SNL, spinal nerve ligation of L5 or L5+ L6. SNI, spared nerve injury. CCI, chronic constriction injury. CFA, injection of Complete Freund’s Adjuvant i

NIAID Data Ecosystem10

Microarray analyses of mouse dorsal root ganglia tissue for six different pain models

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