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Lewis Acid Catalyzed Tandem Polycyclization of Internal Alkynols and Vinyl Azides

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Figshare2016-02-12 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Lewis_Acid_Catalyzed_Tandem_Polycyclization_of_Internal_Alkynols_and_Vinyl_Azides/2112244
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A novel Lewis acid catalyzed tandem cyclization reaction of internal alkynols and vinyl azides has been achieved to afford a series of products containing a pyran-based indeno­[1,2-c]­isochromene scaffold in moderate to high yields. This tandem polycyclization protocol provides a straightforward entry to construct the complex polycyclic skeleton through cycloisomerization, formal [4 + 2] cycloaddition, and an elimination process.
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2016-02-12
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