Multidimensional electrostatic repulsion-hydrophilic interaction chromatography (ERLIC) for quantitative analysis of the proteome and phosphoproteome in clinical and biomedical

Data from ProteomeXchange, PXD ID: PXD001241. Experiment: ERLIC-2 Rep2, file: folder summary. Published as part of Biochim Biophys Acta. 2015 S1570-9639(15)00017-5 . From the Abstract: {{i}} ... we generated a highly sensitive workflow for combined LC-MS-based quantitative proteomics and phosphoproteomics by refining an ERLIC-based 2D phosphoproteomics workflow into an ERLIC-based 3D workflow covering the global proteome as well. The resulting 3D strategy was successfully used for an in-depth quantitative analysis of both, the proteome and the phosphoproteome of murine cytomegalovirus-infected mouse fibroblasts, a model system for host cell manipulation by a virus ... {{/i}}